NATRIUM IONAL CHANNELS SPECIFIC TO THE PERSONAL NERVE SYSTEM, DNA WHICH IT IS CODE, ACTIVE SURVEY AND METHODS OF PRODUCTION AND USE

摘要

Cloning, expression, viral and delivery vectors and hosts which contain nucleic acid coding for at least one peripheral nervous system specific (PNS) sodium channel peptide (SCP), isolated PNS SCP, and compounds and compositions and methods, are provided, for isolating, crystallizing, x-ray analysing molecular modeling, rational drug designing, selecting, making and using therapeutic or diagnostic agents or ligands having at least one peripheral nervous system specific (PNS) sodium channel (SC) modulating activity.