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Process for the preparation of a stable anhydrous ivermectin formulation
Process for the preparation of a stable anhydrous ivermectin formulation
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机译:稳定的无水伊维菌素制剂的制备方法
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摘要
The present invention is directed to a process for preparing a stable anhydrous anthelmintic liquid formulation containing ivermectin, comprising the steps of: UL ST="-" LIpurging the manufacturing vessel with nitrogen gas, LIaltering the pressure of the manufacturing vessel, LIrinsing the manufacturing vessel with isopropyl alcohol, LIadding isopropyl alcohol, ivermectin and a fatty acid ester emollient and mixing, LItesting the solution prior to adding a buffering agent and mixing, LItesting the solution, prior to making up the total volume of the solution to 100% v/v with isopropyl alcohol, LImixing and packaging the formulation. /UL The formulation of the present invention is used for topical administration as a pour-on formulation.
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