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METHOD AND MATERIAL FOR DETECTING SEPSIS AND SEPSIS-LIKE SYSTEMIC INFECTION

机译:检测脓毒症和类似脓毒症的系统感染的方法和材料

摘要

PPROBLEM TO BE SOLVED: To solve the problem that procalcitonin formed in the case of sepsis is provisionally and generally regarded as the same as a calcitonin precursor, therefore, a peptide (procalcitonin 1-116) having a known procalcitonin sequence of 116 amino acids, as analysis assay methods have not clarified the difference between known procalcitonin as the calcitonin precursor and procalcitonin formed in the case of sepsis. PSOLUTION: Recombinant procalcitonin 3-116 can be used for diagnosis and treatment of sepsis and as a marker in measuring prohormones except procalcitonin and dipeptidyl peptidase IV, as well as in diagnosing sepsis. PCOPYRIGHT: (C)2010,JPO&INPIT
机译:

要解决的问题:为了解决在脓毒症中形成的降钙素临时并通常被认为与降钙素前体相同的问题,因此,需要一种具有降钙素原序列已知的肽(降钙素1-1-1)氨基酸,因为分析测定方法尚未阐明作为降钙素前体的已知降钙素与败血症时形成的降钙素之间的差异。

解决方案:重组降钙素3-116可用于败血症的诊断和治疗,并可作为测量降钙素和二肽基肽酶IV以外的激素的指标,以及用于诊断败血症。

版权:(C)2010,日本特许厅&INPIT

著录项

  • 公开/公告号JP2009235090A

    专利类型

  • 公开/公告日2009-10-15

    原文格式PDF

  • 申请/专利权人 BRAHMS AG;

    申请/专利号JP20090152844

  • 申请日2009-06-26

  • 分类号C07K14/585;G01N33/74;C12P21/02;A61K38/23;A61P31/04;

  • 国家 JP

  • 入库时间 2022-08-21 19:46:12

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