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A specific amplification of fetal DNA sequences from maternal sources - fetus is mixed

机译:来自母体的胎儿DNA序列的特定扩增-胎儿混合

摘要

The present invention, the fetus is mixed - provides a method of selectively amplifying a fetal DNA sequence from maternal sources. From the DNA mixture containing a high proportion of non-trophoblast / fetal DNA, the method takes advantage of the differential methylation to allow selective amplification of trophoblast / fetus array. The present invention provides a fetal DNA sequences amplified, have uses for aneuploidy detection.
机译:混合胎儿的本发明提供了一种从母体来源选择性扩增胎儿DNA序列的方法。该方法从含有大量非滋养层/胎儿DNA的DNA混合物中利用差异甲基化优势,可以选择性扩增滋养层/胎儿阵列。本发明提供了扩增的胎儿DNA序列,具有用于非整倍性检测的用途。

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