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Inclusion compounds containing cucurbituril derivatives as host molecules and pharmaceutical compositions containing the same
Inclusion compounds containing cucurbituril derivatives as host molecules and pharmaceutical compositions containing the same
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机译:含有葫芦素衍生物作为主体分子的包合物和含有该化合物的药物组合物
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摘要
The present invention provides an inclusion compound having a cucurbituril derivative of the formula 1 as a host molecule and a metal complex of the formula 2 as a guest molecule. A pharmaceutical composition having an anticancer effect can be obtained by using the inclusion compound according to the present invention. The pharmaceutical composition can prevent effective components from being biologically degraded in vivo and can exhibit continuous drug effect for a long time just by a single dosage by controlling the release time of the platinum complex once it reaches target tumor cells.
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