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Method for improving solubility and dissolution rate in poorly soluble drugs
Method for improving solubility and dissolution rate in poorly soluble drugs
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机译:改善难溶性药物的溶解度和溶解度的方法
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摘要
The present invention relates generally to use of a polyvinyl alcohol-polyethylene glycol graft copolymer (PVA-PEG graft co-polymer), such as Kollicoat IR, in the formulation of solid dispersions of low aqueous solubility and dissolution rate bioactive compound and, more particularly to a system and method for improving the solubility and dissolution rate of such low aqueous solubility and dissolution rate bioactive compound, in particular the drug of low aqueous solubility, such as a BCS Class II or Class IV drug compounds.
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