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Compounds that constitute the effectors of central nervous system receptors that are particularly sensitive to neuroexcitatory amino acids, their production and their biological use
Compounds that constitute the effectors of central nervous system receptors that are particularly sensitive to neuroexcitatory amino acids, their production and their biological use
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机译:构成对神经兴奋性氨基酸,其产生及其生物学用途特别敏感的中枢神经系统受体的效应物的化合物
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摘要
The invention concerns compounds of formula (I):in which: R1 to R4, identical or different, represent hydrogen, alkyl or aryl, themselves substituted if required, R1 and R2 together further capable of representing a bridge -(CH2)m in which m is a whole number from 1 to 5, or a bridge X representing a linear combination of m hydrocarbon groups, m being as defined above and comprising, if required, at least a heteroatom such as O, N or S, or a bridge X representing a linear combination of p heteroatoms O, N and/or S, in which p is a whole number from 1 to 3; A1 and A2 represent -COOH, -SO3H or -PO3H2 radicals, or their derivatives such as esters or amides, or only one of A1 or A2 has these meanings, when R1 and R2 represent a single bond between the carbons in positions 3 and 4, the other of these groups being a hydrogen atom; Y represents a chain -(CH2)n-, n being zero or a whole number from 1 to 5, or represents a linear combination of n hydrocarbon groups and at least a heteroatom O, N or S, or a linear combination of q heteroatoms O, N and/or S, in which q is a whole number from 1 to 3. The invention is applicable as medicines.
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