COMPOUNDS CONSTITUTING IN PARTICULAR CENTRAL NERVOUS SYSTEM RECEPTOR EFFECTORS SENSITIVE TO AMINO NEURO-EXCITER ACIDS, THEIR PREPARATION AND THEIR BIOLOGICAL APPLICATIONS

摘要

The invention concerns compounds of formula (I):in which: R1 to R4, identical or different, represent hydrogen, alkyl or aryl, themselves substituted if required, R1 and R2 together further capable of representing a bridge -(CH2)m in which m is a whole number from 1 to 5, or a bridge X representing a linear combination of m hydrocarbon groups, m being as defined above and comprising, if required, at least a heteroatom such as O, N or S, or a bridge X representing a linear combination of p heteroatoms O, N and/or S, in which p is a whole number from 1 to 3; A1 and A2 represent -COOH, -SO3H or -PO3H2 radicals, or their derivatives such as esters or amides, or only one of A1 or A2 has these meanings, when R1 and R2 represent a single bond between the carbons in positions 3 and 4, the other of these groups being a hydrogen atom; Y represents a chain -(CH2)n-, n being zero or a whole number from 1 to 5, or represents a linear combination of n hydrocarbon groups and at least a heteroatom O, N or S, or a linear combination of q heteroatoms O, N and/or S, in which q is a whole number from 1 to 3. The invention is applicable as medicines.