CEST activity the MRI contrast medium which includes the paramagnetic complex

摘要

This invention offers degree of good impression and at the same time offers the MRI contrast medium which possesses the internal holding time which is optimized. As for these medicines, chemical exchange saturation movement (CEST) the local pH in internal of the patient due to use, temperature, oxygen density, or mapping of the other metabolite are made possible. Especially, mapping of pH and temperature is useful of the respectively, concerning the affected part small cancer and the detection of the inflammation which is localized.