A method of treating a disease associated methods and to diagnose the effect of intergenerational transmission of the epigenetic against mammalian germline of the environment of toxic substances

摘要

The present invention provides a method for detecting a target DNA multigenerational epigenetic mutations caused by (for example, endocrine disrupting chemicals) toxic substances. May either diagnosis and / or treatment by the development of therapeutic agents to a subject by using the present invention, having a DNA mutation identified, to delay the start of the preventing or dysfunction and / or disease closely related possible. None [Selection Figure]