4-chloro for the synthesis of natural carotenoid products 3-methyl-2-butenyl phenyl sulfide, di (4-chloro-3-methyl-2-butenyl) sulfide and di (4-chloro-3-methyl - a process for the preparation of 2-butenyl) sulfone

摘要

Disclosed is a method of preparing intermediates required for synthesis of natural carotenoid products using sulfone compounds, which is advantageous in terms of high preparation efficiency due to a relatively simple process. Specifically, there is provided the preparation method of 4-chloro-3-methyl-2-butenylphenylsulfide as a C5-unit compound for lengthening a carbon chain, and di4-chloro-3-methyl-2-butenylsulfide as a C10-unit compound for forming a central polyene moiety. In addition, di4-chloro-3-methyl-2-butenylsulfone as a selective oxide of the di4-chloro-3-methyl-2-butenylsulfide and a preparation method thereof are provided.