ANETHOLE DERIVATIVE HAVING INFLAMMATORY CYTOKINE PRODUCTION-INHIBITING ACTION, AND FOOD PREPARATION, COSMETIC AND ANTIINFLAMMATORY AGENT COMPRISING THE SAME

摘要

PPROBLEM TO BE SOLVED: To provide an anethole derivative having an excellent inflammatory cytokine production-inhibiting action with weak side effects, and a food preparation, a cosmetic and an antiinflammatory agent each comprising the same. PSOLUTION: The anethole derivative having an inflammatory cytokine production-inhibiting action is a derivative comprised of anethole bonded with any one of palmitic acid, eicosapentaenoic acid, docosahexaenoic acid, docosapentaenoic acid, stearic acid, oleic acid, caprylic acid and anisic acid and is obtained by admixing ground matter of a fruit of anise or a leaf or a seed of a basil with a lipase for transesterification followed by heating and extraction with a vegetable oil or obtained by fermenting the ground matter together with fish and a soybean with bacillus natto followed by extraction with a vegetable oil. The food preparation or the cosmetic comprises the anethole derivative, a vegetable oil containing chrysanthemum extracts and a vegetable oil containing pine needle extracts. The antiinflammatory agent comprises the anethole derivative. PCOPYRIGHT: (C)2009,JPO&INPIT