XANTHONE DERIVATIVE HAVING INHIBITORY ACTION ON INFLAMMATORY CYTOKINE PRODUCTION, METHOD FOR PRODUCING THE SAME AND FOOD PREPARATION, COSMETIC AND ANTI-INFLAMMATORY AGENT COMPRISING THE SAME

摘要

PROBLEM TO BE SOLVED: To obtain a xanthone derivative that has a weak adverse effect and an excellent inhibitory action on inflammatory cytokine production, to provide a method for producing the same and a food preparation, a cosmetic and an anti-inflammatory agent comprising the same.;SOLUTION: The xanthone derivative that has an inhibitory action on inflammatory cytokine production is a derivative obtained by combining xanthone with gluconic acid and a carboxylic acid. The xanthone derivative is acidic, permeates the skin, exhibits an excellent anti-inflammatory action and has high safety. The method for producing the xanthine derivative comprises a process of adding ground soybean and Bacillus natto to ground mangosteen, fermenting the mixture to give a fermented substance and extracting the fermented substance with an acidic aqueous solution. The food preparation and the cosmetic each comprises the xanthone derivative having an inhibitory action on inflammatory cytokine production and a fruit juice essence. The anti-inflammatory agent comprises the xanthone derivative.;COPYRIGHT: (C)2009,JPO&INPIT