Generation of high quantum efficiency generation and one quantitative state oxygen is raised with the candlepower study

摘要

(57) Abstract This invention raises the generation of high quantum efficiency generation and one quantitative state oxygen with lighting, but being the photoactivation possible rhodamine derivative in order containment the relic where desire of the rhodamine between the normal cell and the cancer cell differs, as for the derivative, 4,5 jiburomorodamin 123 (the 2 (4,5 dibromo 6 amino 3 imino 3H xanthein 9 iru) - benzoic acid methyl ester hydrochloric acid); 4,5 jiburomorodamin 123 (2 (4,5 dibromo 6 amino 3 imino 3H xanthein 9 iru) - benzoic acid ethyl ester hydrochloric acid); 4,5 jiburomorodamin 123 (2 (4,5 dibromo 6 amino 3 imino 3H xanthein 9 iru) - benzoic acid octyl ester hydrochloric acid); 4,5 jiburomorodamin 110 (2 (4,5 dibromo 6 amino 3 imino 3H xanthein 9 iru) - benzoic acid n butylester hydrochloric acid); Rhodamine B n butylester (2 (6 ethylamino 3 ethylimino 3H xanthein 9 iru) benzoic acid n butyl ethyl hydrochloric acid); And from the group which consists of those photoactivation possible derivatives choice, and photoactivation of the derivative induces killing and wounding of the cell, but the derivative which is not activated substantially is not poisonous in the cell, it regards the photoactivation possible rhodamine derivative. In addition, it regards the applications of the photoactivation possible rhodamine derivative of main invention in order candlepower study to remedy the cancer patient by the fact that this invention, the level inside the appropriate cell, of the derivative achieving features suitable wavelength and that lighting of strength is applied, breaks the human cancer cell. In addition, this invention regards the candlepower study remedy manner of the patient who contracts a disease in the leukemia, the inside metastatic occurring frequently marrow tumor or the lymph swelling.