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Method for purification of factor VIII / vWF complex by cation exchange chromatography

机译:阳离子交换色谱法纯化凝血因子VIII / vWF复合物的方法

摘要

There is disclosed a method of recovering factor VIII/vWF-complex which is characterized in that factor VIII/vWF-complex from a protein solution is bound to a cation exchanger and is recovered by step-wise elution of factor VIII/vWF-complex, which particularly contains high-molecular vWF multimers, as well as a factor VIII/vWF-complex obtainable by means of cation exchange chromatography.
机译:公开了一种回收因子VIII / vWF-复合物的方法,其特征在于从蛋白质溶液中结合因子VIII / vWF-复合物至阳离子交换剂,并通过逐步洗脱因子VIII / vWF-复合物来回收,其特别包含高分子vWF多聚体,以及可通过阳离子交换色谱法获得的因子VIII / vWF-复合物。

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