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Test Method for MALT Lymphomas and Kit Therefor

机译:MALT淋巴瘤的测试方法及其试剂盒

摘要

An object of the present invention is to provide a test method for MALT lymphomas for providing genetic diagnosis data which can be used for the diagnosis of MALT lymphomas, identification of disease type, and prediction of progression of pathological conditions and onset thereof and a kit for implementing the method. At least two types of tumor-suppressor genes or cancer-related genes are selected, in particular, at least two types of genes are selected from a gene group consisting of 11 genes in a sample, and the expression levels or the gene expression regulation status of the selected genes are investigated. Early detection and diagnosis with high sensitivity and accuracy can be conducted by quantitatively determining the genetic product and preparing the expression profiles of the gene group on the basis of the results, or by detecting methylation frequencies to analyze the expression regulation.
机译:本发明的一个目的是提供一种用于MALT淋巴瘤的测试方法,以提供可用于MALT淋巴瘤的诊断,疾病类型的鉴定以及病理状况和发作的预测的遗传诊断数据,以及一种试剂盒。实现该方法。选择至少两种类型的肿瘤抑制基因或癌症相关基因,特别地,从样品中由11个基因组成的基因组中选择至少两种类型的基因,并且表达水平或基因表达调控状态研究所选基因中的多少。可以通过定量确定遗传产物并根据结果准备基因组的表达谱,或通过检测甲基化频率来分析表达调控,从而进行具有高灵敏度和准确性的早期检测和诊断。

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