Regulators of the non-genomic action of progesterone and methods of use

摘要

A progesterone regulator capable of modulating the non-genomic action of progesterone and methods of using the progesterone regulator are described. The progesterone regulator is useful for attenuating progesterone's inhibition of apoptosis and for the treatment of patients having a progesterone-responsive tissue disease such as endometriosis or cancer, particularly ovarian cancer, as well as for diagnosis, prognosis, and/or staging of ovarian cancers.