A point-based elastic registration method for registering a first image and a second image. Initially, a single control point is randomly placed (S2) with the source image region and optimal parameter settings in respect thereof are determined (S3) for performing elastic deformation (S4) in respect of the first image so as to optimise a similarity measure. Additional control points are then added (S6) one-by-one, and the elastic deformation process repeated each time (S8) in respect of the new control point set, until a predetermined stopping criterion is met, e.g. the resultant improvement in the similarity measure no longer exceeds some predetermined threshold value. Thus, a high speed, high quality registration method is provided without having to specify the number of control points initially.
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