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Altered Intracellular Localization of BRK/Sik Protein Tyrosine Kinase in Human Prostate Tumors
Altered Intracellular Localization of BRK/Sik Protein Tyrosine Kinase in Human Prostate Tumors
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机译:BRK / Sik蛋白酪氨酸激酶在人前列腺肿瘤中的细胞内定位改变。
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摘要
The invention provides methods for detecting abnormal prostate conditions, such as benign prostatic hyperplasia (BPH), prostatic intraepithelial neoplasia (PIN), and adenocarcinoma, in an animal by comparing the amount of the Breast Tumor Kinase (BRK) tyrosine kinase in the nuclei of prostate luminal epithelial cells in a test sample with an amount of nuclear BRK protein in epithelial cells of normal prostate glands.
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