Pharmaceutical Nasal Spray Formulation of Acetaminophen (paracetamol)

摘要

The invention in question is a novel pharmaceutical formulation that comprises a one percent weight by volume Paracetamol in a phosphate buffer adjusted to pH 7.4 by addition of few drops of 1.0 N NaOH. The concentrations of the ingredients were chosen such that the resulting solution is isotonic with body fluids. Said concentrations were theoretically calculated based on their sodium chloride equivalents. The formulation is meant to be used as a nasal spray.