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Selective D1/D5 receptor antagonists for the treatment of obesity and CNS disorders

机译:选择性D 1 / D 5 受体拮抗剂治疗肥胖和中枢神经系统疾病

摘要

The present invention provides compounds, which, are novel antagonists for D1/D5 receptors as well as methods for preparing such compounds. In another embodiment, the invention provides pharmaceutical compositions comprising such D1/D5 receptor antagonists as well as methods of using them to treat CNS disorders, obesity, metabolic disorders, eating disorders such as hyperphagia, and diabetes.
机译:本发明提供了化合物,其是D 1 / D 5 受体的新型拮抗剂以及制备此类化合物的方法。在另一个实施方案中,本发明提供了包含此类D 1 / D 5 受体拮抗剂的药物组合物,以及使用它们治疗中枢神经系统疾病,肥胖症,代谢性疾病,进食的方法。吞噬和糖尿病等疾病。

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