ISOLATED POPULATION OF RAPIDLY PROLIFERATING MARROW STROMAL CELLS FOR ENHANCED IN VIVO ENGRAFTMENT

摘要

Multipotent stromal cells “MSCs” have been described as consisting of at least two populations of cells, rapidly self-renewing stem cells (RS-MSCs), and larger, slowly replicating cells (mMSCs). The present invention provides methods for enhancing engraftment of MSCs in vivo by administering an enriched fraction of RS-MSCs that express certain cell surface markers.