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Recombinant Saccharomyces cerevisiae expressing chimeric glucose transporters

机译:表达酿酒酵母的重组嵌合糖转运蛋白

摘要

The present invention provides a modified Saccharomyces yeast which produces significantly lower levels of ethanol than wild-type yeast under aerobic conditions and saccharide concentrations of 2% glucose, and which exhibits a growth rate of at least 30% of the wild-type yeast, preferably containing a chimeric construct of at least 2 saccharide transporters, nucleic acid molecules encoding the chimeras and polypeptides encoded by such sequences, and methods of using the modified yeast for preparing products in the yeast.
机译:本发明提供了一种修饰的酵母,其在需氧条件下和糖浓度为2%的葡萄糖条件下产生的乙醇水平明显低于野生型酵母,并且其生长速度至少为30%。优选包含至少两种糖转运蛋白的嵌合构建体的野生型酵母,编码嵌合体的核酸分子和由该序列编码的多肽,以及使用修饰的酵母在酵母中制备产物的方法。

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