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Use of calmodulin kinase II inhibitors to treat myocardial dysfunction in structural heart disease
Use of calmodulin kinase II inhibitors to treat myocardial dysfunction in structural heart disease
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机译:钙调蛋白激酶II抑制剂在结构性心脏病中治疗心肌功能障碍的用途
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摘要
The present invention provides a method for treating structural heart disease in a subject, comprising administering an effective amount of an inhibitor of CaMKII to the subject, whereby the administration of the inhibitor treats the structural heart disease in the subject. Also provided are transgenic animal models for treating structural heart disease. Further provided is a means of screening for a compound that can treat structural heart disease.
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