首页> 外国专利> Compositions and combinations of Activator (IS) receptor (PPAR) Activation and Proliferation peroxismal inhibitor of Sterol absorption (IS) the use of said compositions for the manufacture of a Medicament for the treatment for Vascular indications diabetes or Obesity reduction

Compositions and combinations of Activator (IS) receptor (PPAR) Activation and Proliferation peroxismal inhibitor of Sterol absorption (IS) the use of said compositions for the manufacture of a Medicament for the treatment for Vascular indications diabetes or Obesity reduction

机译:激活剂(IS)受体(PPAR)活化和增殖的抗过氧化物甾醇吸收剂(IS)的组合物和组合物,所述组合物在制备用于治疗血管疾病,糖尿病或肥胖症的药物中的用途

摘要

Therapeutic combinations and compositions are provided that include: (a) at least one Activator of peroxisome Proliferation activated receptor; and (b) at least one Sterol Absorption Inhibitor of beta lactam azetidinona replaced or superseded.A composition comprising: (a) a compound represented by the formula (2) or a pharmaceutically acceptable Salt or solvate thereof; (b) lactose Monohydrate microcrystalline Cellulose; (c); (d) povidone croscarmellose sadistic; (e); Sodium lauryl sulfate; (f) and (g) STEARATE Magnesium,Under the condition that the composition comprises: No ingredient Weight percentage of ingredient a compound of formula (2) 10) lactose Monohydrate microcrystalline Cellulose povidone croscarmellose 55 20 8 4 2 sadistic Sodium lauryl sulfate Magnesium Stearate 1 also describes the total 100 or So these compositions and combinations for the manufacture of a Medicament useful for TreatmTreatment of vascular diseases, diabetes, Obesity and reduced plasma levels of Sterols.
机译:提供的治疗组合和组合物包括:(a)至少一种过氧化物酶体增殖活化受体。组合物,其包含:(a)由式(2)表示的化合物或其药学上可接受的盐或溶剂合物;和(b)至少一种取代或取代的β-内酰胺氮杂环丁酮的甾醇吸收抑制剂。 (b)乳糖一水合微晶纤维素; (C); (d)聚乙烯吡咯烷酮虐待狂; (e);月桂基硫酸钠; (f)和(g)硬脂酸镁,在组合物包含的条件下:无成分重量百分比的式(2)化合物的化合物10)乳糖一水合物微晶纤维素聚维酮croscarmellose纤维素55 20 8 4 2施虐的十二烷基硫酸钠硬脂酸镁图1还描述了用于制造可用于治疗血管疾病,糖尿病,肥胖症和降低的甾醇血浆水平的药物的总共100个左右的这些组合物和组合。

著录项

  • 公开/公告号AR064012A2

    专利类型

  • 公开/公告日2009-03-04

    原文格式PDF

  • 申请/专利权人 SCHERING CORPORATION;

    申请/专利号AR2007P105283

  • 发明设计人

    申请日2007-11-28

  • 分类号A61K31/397;A61P3/06;A61P3/10;

  • 国家 AR

  • 入库时间 2022-08-21 19:28:43

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