Crystalline form of 4 - (2 - (4,4 - dimethyl - 2 - oxo - oxazolidin - 3 - il) thiazol-4-yl - 9 Benzonitrile, and Kit containing Pharmaceutical composition, Methods for preparing the forms I and III of 4 - (2 - (4,4 - dimethyl - 2 - oxo - oxazolidin - 3 - il) thiazol-4-yl) benzonitrile and Contraceptive Methods, to Treat or prevent fi

摘要

Claim 1: a Crystalline form of 4 - (2 - (4,4 - dimethyl - 2 - 3 - oxooxazolidin - il) thiazol-4-yl) benzonitrile is characterized by comprising an x-ray diffraction peak in the next Angle (+ / -0.3s) 2 Theta at 12.87 x-rays diffraction Pattern:.Claim 1: a method to prepare the form III of 4 - (2 - (4,4 - dimethyl - 2 - 3 - oxooxazolidin - il) thiazol-4-yl) benzonitrile characterized by understanding: (a) heat the form I of 4 - (2 - (4,Oxooxazolidin - dimethyl - 2 - 4 - 3 - il) thiazol-4-yl) benzonitrile 190 to 195s C; (b) to cool The product of Step (a) to 30 to 40 c at a Speed of 30 to 50 ramp C / minute and (c) heating the product Stage (b) 100 to 110S C.