compound; method for treating a disease or disorder associated with excessive baceous activity in a patient in need thereof; method for modulating bace activity; pharmaceutical composition

摘要

COMPOUND; METHOD FOR TREATMENT OF A DISEASE OR DISORDER ASSOCIATED WITH EXCESSIVE BACE ACTIVITY IN A PATIENT NEEDING IT; METHOD FOR MODULATING BACE ACTIVITY; PHARMACEUTICAL COMPOSITION. The present invention provides an azolylacylguanidine compound of formula I The present invention also provides methods for its use to inhibit β-secretase (BACE) and to treat β-amyloid deposits and neurofibrillary entanglements.