Biologically Active compounds fluorobenzoilo 18F labeled Imaging agents as well as precursors of benzotriazole - 1 - iloxi - Benzoyl - pyrrolidin-3-yl, 2.5 - - 1 - iloxi benzoyl benzoyl and trimethylammonium

摘要

Substituted benzene compounds refers to radioactively labelled images for diagnosis. Provides methods for preparing these Compounds, in particular, to prepare New Compounds that serve as precursors for marking with 18F and the use of these compounds labeled with 18F for Diagnostic Images.Formula (a), where one of Y1, y2, y3, y4 and y5 is - - - A - B - D - P, - A - B - D is a link or a Partition p is a Peptide, a peptidomimetico, an oligonucleotide or a Small Molecule. K or W is LG, LG is selected from the Group comprising formula (b), in which t is H or CL, Q is CH or n, K is absent or C = o, W is a isotpo Radioactive Fluorine, preferably More, 18F.