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System for instant localized delivery of selected agent in gastrointestinal tract

机译:用于在胃肠道中立即局部递送选定药物的系统

摘要

The present invention relates to a system for instant localized delivery of a selected agent in gastrointestinal tract of an animal, whereas said agent contains: a) a core containing said agent and core material, which swells when exposed to an aqueous fluid; and b) a coating surrounding said core, where said coating has an outer surface, comprises water-insoluble hydrophilic particulate matter embedded in a water-insoluble carrier, where said particulate matter forms channels in said coating when said aqueous fluid is present, said channels run from the outer surface of said coating to said core and serve for absorption of said fluid by said core.
机译:本发明涉及一种用于在动物的胃肠道中立即局部递送选择的药剂的系统,而所述药剂包含:a)包含所述药剂和核心材料的核心,当暴露于水性流体时膨胀。 b)围绕所述芯的涂层,其中所述涂层具有外表面,所述涂层包含嵌入不溶于水的载体中的不溶于水的亲水性颗粒物质,当存在所述水性流体时,所述颗粒物在所述涂层中形成通道,所述通道从所述涂层的外表面延伸到所述芯,并用于由所述芯吸收所述流体。

著录项

  • 公开/公告号CZ301028B6

    专利类型

  • 公开/公告日2009-10-14

    原文格式PDF

  • 申请/专利权人 PERIO PRODUCTS LTD.;

    申请/专利号CZ20000001256

  • 申请日1998-10-01

  • 分类号A61K9/28;A61K9/16;A61K9/20;A61K9/52;A61K9/54;A61K9/58;A61K9/62;A61K31/19;A61K31/27;A61K31/407;A61K31/44;A61K45;A61K47/32;A61K47/36;A61K47/38;A61P1;A61P1/06;A61P21/02;A61P29;

  • 国家 CZ

  • 入库时间 2022-08-21 19:28:13

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