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Y4 SELECTIVE RECEPTOR AGONISTS FOR THERAPEUTIC INTERVENTION
Y4 SELECTIVE RECEPTOR AGONISTS FOR THERAPEUTIC INTERVENTION
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机译:Y4介入治疗的选择性受体激动剂
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摘要
Y4 receptor agonists selective for the Y4 receptor over the Y1 and Y2 receptors are useful for treatment of conditions responsive to activation of Y4 receptors. The Y4 selective agonists (a) are PP-fold peptide or PP-fold peptide mimics which have C- and N-terminal sequence features as specified in the description or (b) have an covalent intramolecular link, or (c) comprise two covalently linked C-terminal Y4 receptor-recognition amino acid sequences each of which comprises the last four residues of a C-terminal receptor recognition sequence of the type (a) agonists.
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