CHIMERIC PROTEIN COMPRISING A CELL- TARGETING MOIETY AND AN APOPTOSIS - INDUCING MOIETY OF HUMAN ORIGIN

摘要

The present invention relates to chimeric proteins with cell-targeting specificity and apoptosis-inducing activities. In particular, the invention is illustrated by a recombinant chimeric protein between human interleukin-2 (IL2) and Bax. The chimeric protein specifically targets IL2 receptor (IL2R)-expressing cells and induces cell-specific apoptosis.