A SYNERGISTIC ANTILEUKOTRIENE ANTIHISTAMINIC ANTI-ALLERGY ANTI-INFLAMMATORY COMPOSITION COMPRISING NIMESULIDE AND CETIRIZINE

摘要

An antileukotriene, antihistaminic, antiallergic and anti-inflammatory composition of non-steroidal anti-inflammatory sulfonanilide (NSAID) or their pharmaceutically acceptable salts, esters, polymorphs, isomers, prodrugs, solvates, hydrates, or derivatives thereof as active agent with second generation anti-histamine (Hi blockers) or their pharmaceutically acceptable salts, esters, polymorphs, isomers, prodrugs, solvates, hydrates, or derivatives as active agent alongwith pharmaceutically acceptable base and excipients is provided. More particularly the invention relates to a composition of nimesulide and cetirizine as active agents alongwith pharmaceutically acceptable base and excipients. More particularly the invention relates to a composition for use in allergic disorders namely rhinitis, bronchitis, asthma, urticaria and the like.