Stabilized oral powder / granule comprising of two or more of the 4 anti-TB drugs for Short Course Chemotherapy (SCC), namely Rifampicin, Isoniazid, Ethambutol and Pyrazinamide which can be consumed by mixing in a glass of water or juice with or after the meal is disclosed. Further present invention discloses stabilized oral powder granule compositions of 2 drugs (SCC-2), 3 drugs (SCC-3) and 4 drugs (SCC-4) selected from the said four anti-TB drugs, which are packed in suitable pouches / sachets.
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