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Process for the industrial-scale preparation of a highly purified, standardized human von Willebrand factor concentrate suitable for therapeutic use
Process for the industrial-scale preparation of a highly purified, standardized human von Willebrand factor concentrate suitable for therapeutic use
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机译:工业规模制备适合治疗用途的高度纯化的标准化人von Willebrand因子浓缩物的方法
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摘要
The invention relates to a process for preparing human von Willebrand factor from a plasma cryoprecipitate fraction. The process comprises a combination of three chromatographic separation steps. The concentrate obtained possesses a very high specific activity and a high percentage of multimers of high molecular weight. The concentrate is intended in particular for therapeutic use.
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