3 - (4 - amidopirrol - 2 - ilmetiliden) - 2 - indolinona as inhibitors of the Protein Kinase, Pharmaceutical compositions and a method for Modulation of the catalytic activity of the Protein Kinase; a method for treating or Preventing a disease related protein kinase

摘要

The present invention relates to pyrrole substituted 2-indolinone compounds and their pharmaceutically acceptable salts which modulate the activity of protein kinases and therefore are expected to be useful in the prevention and treatment of protein kinase related cellular disorders such as cancer.