Salts of acid, 4 - 4 - (2R) - 3 - 4 - amino - 2 - Chloro - 5 - (trifluoromethyl) phenyl - 1, 2 - oxo - 4 - (1,2,4,5 - tetrahydro - 2 - oxo - 3H - 1.3 - benzodiazepines - 3 - yl) - 1 - piperidinil carbonyl oxy propyl - 1-piperazinyl piperidin - 1 acid antagonist Peptide (CGRP relates

摘要

AB refers to salts of the base with an Acid B Selected bromhidrico acid, hydrochloric acid, sulfuric acid, among others; as well as the Crystal forms.Compounds are peferidos acid ethyl ester hydrochloride: 4 - [4 - [(2R) - 3 - [4 - amino - 2 - Chloro - 5 - (trifluoromethyl) phenyl] - 2 - oxo - [2 - [[4 - (1,2,4,5 tetrahydro - 2 - oxo - 3H - 1,3 - - benzodiazepine 3 - yl) - piperidinyl] carbonyl] oxy] propyl] - 1-piperazinyl] - 1 - piperidin difumarate acetic acid ethyl ester, 4 - [4 - (2R) - 3 - [4 - amino - 2 - Chloro - 5 - (trifluoromethyl) phenyl] - 2 - oxo - [2 - [[4 - (1,2,4,5 tetrahydro - 2 - oxo - 3H - 1Benzodiazepines - 3 - 3 - yl) - piperidinyl] carbonyl] oxy] propyl] - 1-piperazinyl] piperidin - 1 - acetic acid, among others. It also relates to a method for preparing a Pharmaceutical composition. These salts have antagonist activity of CGRP (gene related Peptide of the calcitocina), being used for the treatment of headaches and migraines especianmente