2 - 3 - (2,2-difluorobenzo-benzene 1,3 dioxo-5-ethylamine) - 5 - (2,6-dimethylpyridine-4-il) - 1,2,4 triazole-1-il - n-acetyl-acetyl and its salts as modulators of α - nicotine receptor

摘要

For compounds 2 - [3 - (2,2-difluorobenzo [1,3] dioxo-5-ethylmethyl) - 5 - (2,6-dimethyl-pyridine-4-il) - [1,2,4] triazole-1-il] - n-ethyl-acetyl-n (I),Salts, hydrates and solutions. A preparation procedure and a drug synthesis were also mentioned. This compound is a Western Sahara modulator positive for acetylcholine A-7 nicotine receptor, which is useful in the treatment of Alzheimer's disease, Lewy's body dementia, Parkinson's disease, etc.