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Ethylene glycol esters and esters of derivatives of monohydrobenzoporphyrins as photoactive agents

机译:乙二醇酯和单氢苯并卟啉衍生物的酯作为光敏剂

摘要

Compounds of the formula CHEM CHEM or the metallated or labeled or conjugated form thereof wherein each R1 is independently alkyl (1-6C); each n is independently an integer of 0-6; and R2 is vinyl or a derivative thereof obtainable by addition or oxidation of the vinyl group; are useful in the manufacture of a photoactive compound for use in photodynamic therapy (PDT) in which the PDT is to treat tumour cells, or to modulate an immune response, to constrict or occlude vasculature or to modulate intracellular signalling.
机译: 的化合物或其金属化或标记或共轭形式,其中每个R 1独立地为烷基(1-6C);每个n独立地是0-6的整数; R 2为乙烯基或可通过乙烯基的加成或氧化得到的衍生物。可用于制造用于光动力疗法(PDT)的光活性化合物,其中PDT用于治疗肿瘤细胞或调节免疫应答,收缩或阻塞脉管系统或调节细胞内信号传导。

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