EXPRESSION AND CHARACTERIZATION OF AN HIV-1 CELL PROTEIN ASSOCIATED WITH A WIDE-REACTIVE NEUTRALIZING ANTIBODY RESPONSE.

摘要

The present invention relates to HIV-1 envelope proteins from a donor with non-progressive HIV-1 infection whose serum contains broadly cross-reactive, primary virus neutralizing antibody. The invention also relates to isolated or purified proteins and protein fragments that share certain amino acids at particular positions with the foregoing HIV-1 proteins.