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MODIFIED HUMANESE MANGANE SUPEROXIDE DISMUTASE AND ITS USES
MODIFIED HUMANESE MANGANE SUPEROXIDE DISMUTASE AND ITS USES
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机译:修饰的人为锰超氧化物歧化酶及其用途
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摘要
The present invention refers to a novel modified form of hMnSOD that can be produced and secreted from cells of human liposarcoma in continuous culture. This protein is obtainable :by ionic exchange chromatography, gel filtration and immunoaffinity techniques from the culture medium in which these cells release it. Moreover the present invention refers to the use of this modified hMnS.OD for preparation of a medicament for prevention and therapy of tumors, of septic and traumatic shock, diabetic neuropathy, post-herpetic neuritis and malignant hyperthermia and for healing of cutaneous lesions.
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