HAPTEN-CARRIER MULTIVALENT COMPLEXES WITH DENDRIMEROS AS EMULATORS OF THE CARRIER PROTEIN.

摘要

The present invention relates to the production of multivalent hapten-carrier complexes, in which the carrier protein is emulated by a dendrimer or dendrimeric molecule, which acts as a carrier macromolecule on which the single or combined hapten of different drugs covalently binds. or chemical structures. These multivalent hapten-carrier complexes can be used, coupled to solid or soluble phase, as antigenic structures for the uptake of IgE antibodies specific for beta-lactam antibiotics and other drugs, allowing their application in in vitro diagnostic techniques that evaluate the allergic reactions, also being applicable in immunoassay type analysis systems.