MANUFACTURE OF A QUICKLY DISINTEGRABLE PRESENTATION, FROM A POWDER SOLID, AND A LIOFILIZATION STAGE.

摘要

A method of manufacturing solid dosage forms, of rapid disintegration, characterized by the fact that one or more building components of the structure, in the form of solid powder mixture, are dosed into the cavities of packaging of strips of packaging blisters, or molds, are dosed and the remaining components, dissolved in water, are added to the solid powder mixture, to form a moistened, plasticized mass, frozen at a temperature below a level of -20 ° C, and the water is sublimated under high vacuum.