COMPOSITIONS CONTAINING AN OX-40 RECEIVER UNION AGENT OR A NUCLEID ACID THAT CODIFIES THE SAME AND PROCEDURES TO POWER THE SPECIFIC IMMUNE ANTIGEN RESPONSE.

摘要

Use of a binding agent that specifically binds to an OX40 receptor, said binding agent being an OX-40L, a functional domain of OX40L, a fusion protein comprising OX40L or a functional domain of OX40L, an anti-OX antibody -40, or an immunologically effective portion of an anti-OX-40 antibody, in the manufacture of a pharmaceutical composition intended for the treatment of a mammal to improve by administration the immune response against a specific antigen chosen in the mammal such that said binding agent is presented to mammalian T cells during or shortly after sensitization of the T cells by said antigen or while said antigen is being presented to T cells.