Locus chromosomal for strict control of gene activities by way of transcription activation systems.

摘要

A vector for transgenesis of a mammalian cell or a mammalian organism by homologous recombination, said vector comprising at least one transcription unit containing the gene to be introduced into the genome and sequences flanking the or transcription units , wherein the flanking sequences are selected so that homologous recombination occurs in the LC-1 locus mammal in mouse is characterized by any one of SEQ ID Nos. 1 to 4.