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HAPTEN-CARRIER CONJUGATES FOR USE IN DRUG-ABUSE THERAPY AND METHODS FOR PREPARATION OF SAME

机译:用于药物滥用治疗的半抗原载体缀合物及其制备方法

摘要

Hapten-carrier conjugates capable of eliciting anti-haptenanti--bodies in vivo are described. Methods of preparing said conjugates andtherapeutic compositions are also described. Where the hapten is a drugof abuse, a therapeutic composition containing the hapten-carriercon-jugate is particularly useful in the treatment of a drug addiction. Thetherapeutic composition is suitable for co-therapy with otherconven-tional drugs. Passive immunization using antibodies raised against thehapten-carrier conjugates of the invention are also described.
机译:能够引发抗半抗原的半抗原-载体缀合物描述了体内抗体。制备所述缀合物的方法和还描述了治疗组合物。半抗原是药物的地方含有半抗原载体的治疗组合物结合物在药物成瘾的治疗中特别有用。的治疗组合物适合与其他药物联合治疗常规药物。使用针对该抗体的抗体进行被动免疫还描述了本发明的半抗原-载体缀合物。

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