REPAIR AND TREATMENT OF BONE DEFECT BY USING CELLS INDUCED BY FACTOR PRODUCED BY CHONDROCYTE HAVING HYPERTROPHIC ABILITY AND SCAFFOLD

摘要

Disclosed is a method for inducing an undifferentiated cell into an induced osteoblast. The method comprises the following steps A) and B): A) providing an induced osteoblast differentiation induction factor prepared by culturing a chondrocyte having a hypertrophic ability in a differentiation factor production medium supplemented with dexamethasone, β-glycerophosphate, ascorbic acid and a serum component; and B) culturing an undifferentiated cell in an undifferentiated cell culture medium containing the induced osteoblast differentiation induction factor and medium components, thereby differentiating the undifferentiated cell into the induced osteoblast.