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METHOD FOR QUANTITATIVELY DETERMINING THE LDL PARTICLE NUMBER IN A DISTRIBUTION OF LDL CHOLESTEROL SUBFRACTIONS
METHOD FOR QUANTITATIVELY DETERMINING THE LDL PARTICLE NUMBER IN A DISTRIBUTION OF LDL CHOLESTEROL SUBFRACTIONS
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机译:LDL胆固醇取代基分布中LDL粒子数的定量测定方法
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摘要
The invention provides a method (e.g., a computer algorithm) for calculating a number of particles in a LDL subfraction. The method features the steps of: 1) measuring an initial distribution of LDL particles (e.g., a relative mass distribution) from a blood sample; 2) processing the initial distribution of LDL particles with a mathematical model to determine a modified distribution of LDL particles (e.g., a relative particle distribution); 3) determining a total LDL particle number value from a blood sample; and 4) analyzing both the modified distribution of particles and the total LDL particle number value to calculate the particle number value in an LDL subfraction.
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