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HYDROXYLATED LONG-CHAIN RESVERATROL DERIVATIVES USEFUL AS NEUROTROPHIC AGENTS

机译:可用作神经营养剂的羟基化长链白藜芦醇衍生物

摘要

The present invention relates to a compound of general formula (I) below in which R1, R2 and R3 represent, independently of one another, a hydrogen atom or a C1-C6 alkyl group or a (C1-C6 alkyl)carbonyl group, R4, R5, R6 and R7 represent a hydrogen or a C1-C6 alkyl group, a C1-C6 alkoxy group or a (C1-C6 alkyl)carbonyloxy group, and n is an integer between 8 and 20, or its pharmaceutically acceptable addition salts, isomers, enantiomers and diastereoisomers, and also mixtures thereof. The invention also relates to a pharmaceutical composition comprising the compound and to the use thereof as a neurotrophic agent.
机译:本发明涉及以下通式(I)的化合物,其中R 1,R 2和R 3彼此独立地表示氢原子或C 1 -C 6烷基或(C 1 -C 6烷基)羰基。 ,R 5,R 6和R 7表示氢或C 1 -C 6烷基,C 1 -C 6烷氧基或(C 1 -C 6烷基)羰氧基,并且n为8至20之间的整数,或其药学上可接受的加成盐。异构体,对映异构体和非对映异构体,以及它们的混合物。本发明还涉及包含该化合物的药物组合物及其作为神经营养剂的用途。

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