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USE OF GOSERELIN AND AMYLIN AS THERAPEUTIC AGENTS

机译:使用戈塞瑞林和淀粉酶作为治疗剂

摘要

The present invention is directed to the use of the peptide compound Pyr-His-Trp-Ser-Tyr-D-Ser(tBu)-Leu-Arg-Pro-Azagly-NH2 as a therapeutic agent for the prophylaxis and/or treatment of cancer, autoimmune diseases, fibrotic diseases, inflammatory diseases, neurodegenerative diseases, infectious diseases, lung diseases, heart and vascular diseases and metabolic diseases. Moreover the present invention relates to pharmaceutical compositions preferably in form of a lyophilisate or liquide buffer solution or artificial mother milk formulation or mother milk substitute containing the peptide Pyr-His-Trp-Ser-Tyr-D-Ser(tBu)-Leu-Arg-Pro-Azagly-NH2 optionally together with at least one pharmaceutically acceptable carrier, cryoprotectant, lyoprotectant, excipient and/or diluent.
机译:本发明涉及肽化合物Pyr-His-Trp-Ser-Tyr-D-Ser(tBu)-Leu-Arg-Pro-Azagly-NH 2作为治疗剂用于预防和/或治疗糖尿病的用途。癌症,自身免疫性疾病,纤维化疾病,炎性疾病,神经退行性疾病,传染病,肺部疾病,心脏和血管疾病以及代谢性疾病。此外,本发明涉及药物组合物,其优选为冻干物或液体缓冲溶液或人工母乳制剂或人工母乳制剂的形式,其包含肽Pyr-His-Trp-Ser-Tyr-D-Ser(tBu)-Leu-Arg -氮杂原-NH 2任选地与至少一种药学上可接受的载体,冷冻保护剂,冻干保护剂,赋形剂和/或稀释剂一起。

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