COMBINATIONS OF (1R, 2R, 3S, 4S) -N4- (3-AMINOCARBONYLBICYCLO 2. 2. 1 HEPT-5-ENE-2-YL) - 5-FLUORO-N2- ( 3 - METHYL-4- (4 -METHYLPIPERAZIN-1-YL PHENYL-2, 4-PYRIMIDINEAMINE

摘要

The invention relates to combinations of (1 R,2R,3S,4S)-N4-(3- aminocarbonylbicyclo[2.2.1]hept-5-ene-2-yl)-5-fluoro-N2-[(3-nnethyl-4-(4- methylpiperazin-1 -yl)]phenyl-2,4-pyrimidinediamine and/or its physiologically acceptable salts and solvates, and other cancer therapeutics, and the use of such combinations for the treatment of cancer.